Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
pcPyruvate carboxylase b. (1048 aa)    
Predicted Functional Partners:
me1
Malic enzyme.
   
 0.982
LOC101155546
Malic enzyme.
   
 0.982
me2
Malic enzyme.
   
 0.982
Mdh2
Malate dehydrogenase.
  
 0.982
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.981
LOC101156855
Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.978
LOC101163391
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.974
hlcs
Holocarboxylase synthetase.
  
 
 0.972
pck2
Phosphoenolpyruvate carboxykinase 2 (mitochondrial).
   
 
 0.970
LOC101165776
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.967
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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