Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hlcsHolocarboxylase synthetase. (916 aa)    
Predicted Functional Partners:
pc
Pyruvate carboxylase b.
  
 
 0.972
LOC101173953
Biotinidase.
    
 0.945
pccb
Propionyl-CoA carboxylase subunit beta.
  
 
 0.894
nfkbid
ANK_REP_REGION domain-containing protein.
      
 0.852
pcca
Propionyl-CoA carboxylase subunit alpha.
    
 0.832
mccc1
Methylcrotonoyl-CoA carboxylase 1 (alpha).
    
 0.832
Sdhaf1
Succinate dehydrogenase complex assembly factor 1; Belongs to the complex I LYR family.
      
 0.813
acacb
Acetyl-CoA carboxylase beta.
  
 0.809
LOC101155873
Acetyl-CoA carboxylase alpha.
  
 0.809
ENSORLP00000037982
Uncharacterized protein.
  
 0.809
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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