Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC1000495291-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)    
Predicted Functional Partners:
LOC101168718
Uncharacterized protein.
    
 0.968
LOC101158934
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.968
LOC101167719
Uncharacterized protein.
    
 0.948
LOC101162627
G protein-coupled receptor, class C, group 6, member A.
     
 0.925
casr
Calcium-sensing receptor.
     
 0.925
LOC105357196
G_PROTEIN_RECEP_F3_4 domain-containing protein.
     
 0.925
inpp1
Si:ch211-160o17.2.
    
 0.912
calm3
Calmodulin-A; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
     
 0.910
mtm1
Myotubularin 1.
     
 0.906
LOC101168465
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.903
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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