Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tyk2Tyrosine-protein kinase. (1169 aa)    
Predicted Functional Partners:
LOC101154761
Signal transducer and activator of transcription.
   
 0.996
LOC101173855
Signal transducer and activator of transcription.
   
 0.995
socs3
Suppressor of cytokine signaling 3a.
   
 0.978
socs3-2
Uncharacterized protein.
   
 0.978
stat3
Signal transducer and activator of transcription.
   
 0.944
LOC101162184
Signal transducer and activator of transcription.
   
 0.938
LOC101161521
Signal transducer and activator of transcription.
   
 0.932
LOC101158490
Signal transducer and activator of transcription.
    
 0.932
jak1
Tyrosine-protein kinase.
  
  
0.918
ifngr1
Uncharacterized protein.
     
 0.917
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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