Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CDC37Cell division cycle 37 homolog (S. cerevisiae). (369 aa)    
Predicted Functional Partners:
LOC101169506
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
   
 0.935
hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
   
 0.928
stip1
Stress-induced phosphoprotein 1.
   
 
 0.871
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.867
pink1
PTEN induced kinase 1.
    
 
 0.815
ppp5c
Serine/threonine-protein phosphatase.
    
 
 0.793
cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.
   
 
 0.777
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 
 0.774
trap1
TNF receptor-associated protein 1.
   
 0.734
tsc1
TSC complex subunit 1b.
   
 0.725
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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