Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACSF3Acyl-CoA synthetase family member 3. (627 aa)    
Predicted Functional Partners:
mlycd
Malonyl-CoA decarboxylase.
   
 0.959
H2MEE3_ORYLA
Carrier domain-containing protein.
  
 0.955
aox1
Aldehyde oxidase beta.
     
 0.954
LOC101155544
Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family.
  
 0.938
aldh16a1
Aldehyde dehydrogenase 16 family, member A1.
  
 0.938
aldh9a1
4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.
  
 0.938
aldh2
Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family.
  
 0.938
mcee
Methylmalonyl CoA epimerase.
  
 
 0.936
LOC101156839
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
LOC101160930
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (8%) [HD]