Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
liasLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (409 aa)    
Predicted Functional Partners:
LOC101170349
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae).
  
 0.997
lipt1
Lipoyltransferase 1.
  
 
 0.995
lipt2
Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family.
 
 
 0.995
LOC101156637
Glycine cleavage system protein H (aminomethyl carrier), b.
 
 0.944
LOC101155190
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
  
 0.933
LOC101168346
Zgc:110319.
  
 0.909
dlat
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.899
pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.823
fdx1
2Fe-2S ferredoxin-type domain-containing protein.
    
 0.818
fdx2
Ferredoxin 2.
    
 0.784
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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