Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
clpxCaseinolytic mitochondrial matrix peptidase chaperone subunit b. (624 aa)    
Predicted Functional Partners:
clpp
ATP-dependent Clp protease proteolytic subunit.
 0.999
lonp2
Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-.
 
 
 0.961
hspd1
Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family.
  
 0.885
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.882
afg3l2
AFG3-like AAA ATPase 2.
  
  
 0.879
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
  
  
 0.869
LOC100049501
5-aminolevulinate synthase.
   
 0.836
atp5f1b
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
   
 0.833
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
     
 0.828
tfam
Transcription factor A, mitochondrial.
   
 
 0.815
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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