Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC101174230Receptor protein-tyrosine kinase. (1292 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.988
egf
Epidermal growth factor.
   
 0.978
LOC101160461
EGF-like domain-containing protein.
    
 0.976
SHC3
SHC adaptor protein 3.
    
 0.968
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.968
SHC4
SHC adaptor protein 4.
    
 0.968
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.964
shc2
SHC (Src homology 2 domain containing) transforming protein 2.
    
 0.958
LOC101171502
Uncharacterized protein.
    
 0.947
ptk2
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
0.940
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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