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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101169556ADAM metallopeptidase domain 12. (955 aa)    
Predicted Functional Partners:
VASH1
Vasohibin 1.
      
 0.585
EBF1
EBF transcription factor 1.
      
 0.518
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
      
 0.516
cilp2
Cartilage intermediate layer protein 2.
      
 0.508
ccn4
Cellular communication network factor 4a.
      
 0.501
LOC101170815
Tenascin C.
   
  
 0.459
eapp
E2f-associated phosphoprotein.
      
 0.433
LOC101162765
EBF transcription factor 1.
      
 0.410
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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