STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF146Ring finger protein 146. (375 aa)    
Predicted Functional Partners:
LOC101158122
Poly [ADP-ribose] polymerase.
    
 0.955
LOC105353570
Poly [ADP-ribose] polymerase.
    
 0.901
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.708
parp2
Poly [ADP-ribose] polymerase.
    
 
 0.698
trip12
Thyroid hormone receptor interactor 12.
      
 0.670
axin1
Axin 1.
    
 0.657
LOC101159441
Axin 2 (conductin, axil).
    
 0.657
AXIN2
Axin 2.
    
 0.657
LOC101155494
Uncharacterized protein.
    
 0.657
rps27a
Ribosomal protein S27a.
   
  0.641
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.