STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ist1IST1 factor associated with ESCRT-III. (346 aa)    
Predicted Functional Partners:
chmp2a
Charged multivesicular body protein 2A.
   
 0.991
chmp2b
Charged multivesicular body protein 2Bb.
   
 0.983
chmp3
Charged multivesicular body protein 3.
    
 0.983
chmp1b
Chromatin modifying protein 1B.
   
 
 0.980
vta1
Vesicle (multivesicular body) trafficking 1.
   
 
 0.974
spast
Spastin; Belongs to the AAA ATPase family.
    
 0.968
LOC101160809
Acylaminoacyl-peptide hydrolase.
    
 
 0.939
LOC101171319
Uncharacterized protein; Belongs to the AAA ATPase family.
   
 0.934
vps4a
Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.
   
 0.934
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
   
 0.934
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.