Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbxo45F-box protein 45. (288 aa)    
Predicted Functional Partners:
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.969
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.967
Mycbp2
RING-type domain-containing protein.
    
 
 0.956
H2M7E3_ORYLA
Uncharacterized protein.
    
 
 0.955
kctd6
Potassium channel tetramerization domain containing 6b.
     
 0.880
SPRYD3
SPRY domain containing 3.
    
 
 0.877
LOC101156411
SPRY domain containing 3.
    
 
 0.877
fbxo9
F-box protein 9.
     
 0.828
LOC101172920
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.806
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.806
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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