Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RAP2BRAP2B, member of RAS oncogene family. (186 aa)    
Predicted Functional Partners:
LOC101167824
Zgc:171558.
   
 0.736
ENSORLP00000030507
Rap guanine nucleotide exchange factor (GEF) 4.
   
 0.736
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
    
 0.720
LOC101158525
Rap guanine nucleotide exchange factor (GEF) 3.
    
 0.660
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.642
araf
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.642
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.642
LOC101155291
Signal-induced proliferation-associated 1.
    
 0.597
grb2
Growth factor receptor-bound protein 2b.
   
 0.592
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
    
 0.583
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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