STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSTM4Glutathione S-transferase mu 4; Belongs to the GST superfamily. (254 aa)    
Predicted Functional Partners:
gss
Glutathione synthetase.
   
 0.933
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
 0.928
cyp1a
Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
   
 
 0.915
GPX4
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.914
LOC101159216
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.910
txndc12
Thioredoxin domain containing 12 (endoplasmic reticulum).
   
  0.900
LOC101171103
Uncharacterized protein; Belongs to the GST superfamily.
   
 0.878
LOC101171354
Uncharacterized protein; Belongs to the GST superfamily.
   
 0.878
LOC101170897
Glutathione S-transferase theta 2; Belongs to the GST superfamily.
    
 0.877
LOC101173040
Glutathione S-transferase theta 1a; Belongs to the GST superfamily.
    
 0.877
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.