STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1207 aa)    
Predicted Functional Partners:
dlg3
Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family.
    
 0.920
Nedd4
Uncharacterized protein.
     
 
0.900
rps27a
Ribosomal protein S27a.
    
  0.833
ubc
Ubiquitin B.
    
 0.824
LOC101169984
Receptor protein-tyrosine kinase.
    
 0.818
egfr
Receptor protein-tyrosine kinase.
    
 0.818
ndfip2
Nedd4 family interacting protein 2.
    
 
 0.815
LOC101169307
Angiomotin.
    
 0.794
LOC101170140
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.781
LOC101163560
Tyrosine-protein kinase receptor.
   
 0.774
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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