STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpnHepsin; Belongs to the peptidase S1 family. (427 aa)    
Predicted Functional Partners:
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
  
 
 
0.646
LOC101168450
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
  
 
 
0.638
ENSORLP00000031012
Kringle domain-containing protein.
   
 
  0.614
kcnk18
Potassium channel, subfamily K, member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.604
LOC101175393
Macrophage stimulating 1 receptor a.
    
 0.599
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.599
mst1r
Macrophage stimulating 1 receptor b.
    
 0.599
LOC101166010
Tectorin beta.
      
 0.589
LOC101174207
Aryl hydrocarbon receptor interacting protein-like 1.
      
 0.583
LOC101164740
Fork-head domain-containing protein.
     
 0.578
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.