Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2LNT0_ORYLA3-hydroxybutyrate dehydrogenase, type 2. (102 aa)    
Predicted Functional Partners:
oxct1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 0.935
LOC101169570
3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.931
hmgcll1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.
   
 
 0.929
hmgcl
3-hydroxy-3-methylglutaryl-CoA lyase.
   
 
 0.929
aacs
Acetoacetyl-CoA synthetase.
  
 
 0.928
acaa1
Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.713
eci2
Enoyl-CoA delta isomerase 2.
  
 0.643
LOC101155544
Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family.
  
 0.574
hao2
Hydroxyacid oxidase 2 (long chain).
   
 0.571
ehhadh
Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.556
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (12%) [HD]