Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prps1Phosphoribosyl pyrophosphate synthetase 1B. (320 aa)    
Predicted Functional Partners:
ppat
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.953
rpia
Ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase).
  
 
 0.947
rbks
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.947
LOC101162749
Transketolase a.
   
 
 0.941
TKT
Transketolase.
   
 
 0.941
LOC101158764
Transketolase b.
   
 
 0.941
pgm2
Phosphoglucomutase 2.
  
 0.936
nudt9
Nudix (nucleoside diphosphate linked moiety X)-type motif 9.
     
 0.926
umps
Uridine monophosphate synthetase.
  
 
 0.926
LOC101175508
Uncharacterized protein; Belongs to the phosphohexose mutase family.
   
 
 0.923
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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