Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kpna4Importin subunit alpha; Belongs to the importin alpha family. (520 aa)    
Predicted Functional Partners:
cse1l
CSE1 chromosome segregation 1-like (yeast).
   
 0.972
kpna1
Importin subunit alpha; Belongs to the importin alpha family.
  
0.945
nfkb1
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.
    
  0.938
kpnb1
Karyopherin (importin) beta 1.
   
 0.936
LOC101158728
V-rel avian reticuloendotheliosis viral oncogene homolog A.
   
  0.932
kpna3
Importin subunit alpha; Belongs to the importin alpha family.
  
  
 
0.900
rcc1
Regulator of chromosome condensation 1.
   
 
 0.867
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 
 0.761
prpf19
Pre-mRNA processing factor 19.
   
   0.749
LOC101160447
RAN binding protein 2.
   
 
 0.701
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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