STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (437 aa)    
Predicted Functional Partners:
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.931
LOC101168152
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.931
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 0.931
pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.931
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.930
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.927
LOC101155144
Uncharacterized protein.
    
 0.927
H2MSU3_ORYLA
Uncharacterized protein.
    
 0.927
LOC101163728
Uncharacterized protein.
    
 0.927
pik3r3
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.927
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.