Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101173869Inositol polyphosphate-5-phosphatase Jb. (469 aa)    
Predicted Functional Partners:
aspm
Abnormal spindle microtubule assembly.
    
 
 0.652
mad2l1bp
MAD2L1 binding protein.
    
 
 0.634
LOC101171587
Inositol polyphosphate-5-phosphatase L.
   
  
 0.608
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
   
 
 0.600
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
   
 
 0.600
synj1
Synaptojanin 1.
    
 0.549
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 0.534
gak
Cyclin G associated kinase.
   
 
 0.529
mtg2
Mitochondrial ribosome-associated GTPase 2.
      
 0.506
LOC101165168
RAB34, member RAS oncogene family b.
   
 
 0.497
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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