STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101168864P53-induced death domain protein 1. (1004 aa)    
Predicted Functional Partners:
LOC101164618
CASP2 and RIPK1 domain containing adaptor with death domain.
    
 0.983
casp2
Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.978
LOC101172563
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
  0.758
cask
Uncharacterized protein; Belongs to the MAGUK family.
    
  0.758
LOC101155756
LIM domain-containing protein.
    
 0.711
LOC101164852
LIM domain-containing protein.
    
 0.711
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.
    
 0.703
LOC101170553
NME/NM23 family member 8; Belongs to the NDK family.
   
 0.679
ubxn7
UBX domain protein 7.
    
 0.677
ENSORLP00000027619
TAN domain-containing protein.
    
 0.671
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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