plek protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

plek

Pleckstrin. (350 aa)

Predicted Functional Partners:

fermt3

0.745

rabif

0.723

plcg1

0.620

carmil1

0.617

rasa1

0.611

mtg2

0.611

tyrobp

0.586

CDC42

0.552

LOC101164400

0.552

H2MN86_ORYLA

0.535

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	H2MN86_ORYLA	ENSORLP00000015084	ENSORLP00000020187	Cell division cycle 42.	ADP-ribosylation factor 6b.	0.519
CDC42	plek	ENSORLP00000015084	ENSORLP00000008015	Cell division cycle 42.	Pleckstrin.	0.552
CDC42	rabif	ENSORLP00000015084	ENSORLP00000033240	Cell division cycle 42.	RAB interacting factor.	0.737
CDC42	rasa1	ENSORLP00000015084	ENSORLP00000012485	Cell division cycle 42.	RAS p21 protein activator (GTPase activating protein) 1a.	0.731
H2MN86_ORYLA	CDC42	ENSORLP00000020187	ENSORLP00000015084	ADP-ribosylation factor 6b.	Cell division cycle 42.	0.519
H2MN86_ORYLA	LOC101164400	ENSORLP00000020187	ENSORLP00000034529	ADP-ribosylation factor 6b.	Uncharacterized protein.	0.519
H2MN86_ORYLA	plek	ENSORLP00000020187	ENSORLP00000008015	ADP-ribosylation factor 6b.	Pleckstrin.	0.535
H2MN86_ORYLA	rabif	ENSORLP00000020187	ENSORLP00000033240	ADP-ribosylation factor 6b.	RAB interacting factor.	0.738
H2MN86_ORYLA	rasa1	ENSORLP00000020187	ENSORLP00000012485	ADP-ribosylation factor 6b.	RAS p21 protein activator (GTPase activating protein) 1a.	0.597
LOC101164400	H2MN86_ORYLA	ENSORLP00000034529	ENSORLP00000020187	Uncharacterized protein.	ADP-ribosylation factor 6b.	0.519
LOC101164400	plek	ENSORLP00000034529	ENSORLP00000008015	Uncharacterized protein.	Pleckstrin.	0.552
LOC101164400	rabif	ENSORLP00000034529	ENSORLP00000033240	Uncharacterized protein.	RAB interacting factor.	0.611
LOC101164400	rasa1	ENSORLP00000034529	ENSORLP00000012485	Uncharacterized protein.	RAS p21 protein activator (GTPase activating protein) 1a.	0.731
carmil1	plek	ENSORLP00000036092	ENSORLP00000008015	Uncharacterized protein.	Pleckstrin.	0.617
fermt3	plek	ENSORLP00000003139	ENSORLP00000008015	Fermitin family member 3b.	Pleckstrin.	0.745
mtg2	plek	ENSORLP00000014774	ENSORLP00000008015	Mitochondrial ribosome-associated GTPase 2.	Pleckstrin.	0.611
plcg1	plek	ENSORLP00000030443	ENSORLP00000008015	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Pleckstrin.	0.620
plcg1	rasa1	ENSORLP00000030443	ENSORLP00000012485	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	RAS p21 protein activator (GTPase activating protein) 1a.	0.614
plcg1	tyrobp	ENSORLP00000030443	ENSORLP00000040436	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	Uncharacterized protein.	0.409
plek	CDC42	ENSORLP00000008015	ENSORLP00000015084	Pleckstrin.	Cell division cycle 42.	0.552