STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sordSorbitol dehydrogenase. (354 aa)    
Predicted Functional Partners:
xylb
Xylulokinase homolog (H. influenzae).
  
 
 0.958
adhfe1
Alcohol dehydrogenase iron containing 1.
  
 
 0.952
coq2
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
  
 
 0.937
LOC101167259
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2.
  
 0.936
HK1
Hexokinase 1.
   
 
 0.927
LOC101156878
Hexokinase 1.
   
 
 0.927
LOC101166309
Hexokinase 2.
   
 
 0.927
LOC101165960
Phosphotransferase.
   
 
 0.927
esd
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
 
 0.919
dcxr
Dicarbonyl/L-xylulose reductase.
   
 
 0.919
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (24%) [HD]