STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
shbgSex hormone-binding globulin. (378 aa)    
Predicted Functional Partners:
gabpa
GA binding protein transcription factor subunit alpha.
      
 0.752
atp5pf
ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.
    
 
 0.750
amh
Anti-muellerian hormone.
      
 0.694
LOC101171978
Si:ch211-140m22.7.
    
 
 0.555
dr1
Down-regulator of transcription 1.
      
 0.536
LOC101154983
Fragile X mental retardation, autosomal homolog 2.
      
 0.527
fxr1
Fragile X mental retardation, autosomal homolog 1.
      
 0.527
cyp17
Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction; Belongs to the cytochrome P450 family.
      
 0.490
LOC101174651
Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
   
  
 0.472
cyp19b
Aromatase B; Belongs to the cytochrome P450 family.
   
  
 0.472
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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