Topors protein (Oryzias latipes) - STRING interaction network

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Score

Topors

Topoisomerase I binding, arginine/serine-rich a. (680 aa)

Predicted Functional Partners:

sumo1

0.815

tp53

0.789

ubxn7

0.770

LOC101169703

0.755

ube2i

0.755

mtap

0.730

LOC101164703

0.668

LOC101160181

0.636

spina

0.636

kctd2

0.615

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101160181	Topors	ENSORLP00000024545	ENSORLP00000008114	Spindlin a.	Topoisomerase I binding, arginine/serine-rich a.	0.636
LOC101164703	Topors	ENSORLP00000008059	ENSORLP00000008114	Programmed cell death 4a.	Topoisomerase I binding, arginine/serine-rich a.	0.668
LOC101164703	mtap	ENSORLP00000008059	ENSORLP00000042253	Programmed cell death 4a.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.793
LOC101169703	Topors	ENSORLP00000016945	ENSORLP00000008114	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Topoisomerase I binding, arginine/serine-rich a.	0.755
LOC101169703	sumo1	ENSORLP00000016945	ENSORLP00000000767	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.993
LOC101169703	tp53	ENSORLP00000016945	ENSORLP00000008031	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.928
LOC101169703	ube2i	ENSORLP00000016945	ENSORLP00000045538	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.900
LOC101169703	ubxn7	ENSORLP00000016945	ENSORLP00000031501	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBX domain protein 7.	0.404
Topors	LOC101160181	ENSORLP00000008114	ENSORLP00000024545	Topoisomerase I binding, arginine/serine-rich a.	Spindlin a.	0.636
Topors	LOC101164703	ENSORLP00000008114	ENSORLP00000008059	Topoisomerase I binding, arginine/serine-rich a.	Programmed cell death 4a.	0.668
Topors	LOC101169703	ENSORLP00000008114	ENSORLP00000016945	Topoisomerase I binding, arginine/serine-rich a.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.755
Topors	kctd2	ENSORLP00000008114	ENSORLP00000027547	Topoisomerase I binding, arginine/serine-rich a.	Potassium channel tetramerization domain containing 2.	0.615
Topors	mtap	ENSORLP00000008114	ENSORLP00000042253	Topoisomerase I binding, arginine/serine-rich a.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.730
Topors	spina	ENSORLP00000008114	ENSORLP00000028361	Topoisomerase I binding, arginine/serine-rich a.	Spindlin protein A.	0.636
Topors	sumo1	ENSORLP00000008114	ENSORLP00000000767	Topoisomerase I binding, arginine/serine-rich a.	Small ubiquitin-related modifier.	0.815
Topors	tp53	ENSORLP00000008114	ENSORLP00000008031	Topoisomerase I binding, arginine/serine-rich a.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.789
Topors	ube2i	ENSORLP00000008114	ENSORLP00000045538	Topoisomerase I binding, arginine/serine-rich a.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.755
Topors	ubxn7	ENSORLP00000008114	ENSORLP00000031501	Topoisomerase I binding, arginine/serine-rich a.	UBX domain protein 7.	0.770
kctd2	Topors	ENSORLP00000027547	ENSORLP00000008114	Potassium channel tetramerization domain containing 2.	Topoisomerase I binding, arginine/serine-rich a.	0.615
kctd2	sumo1	ENSORLP00000027547	ENSORLP00000000767	Potassium channel tetramerization domain containing 2.	Small ubiquitin-related modifier.	0.912