Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
slc19a1Solute carrier family 19 member 1. (496 aa)    
Predicted Functional Partners:
tpmt
Thiopurine S-methyltransferase, tandem duplicate 1.
      
 0.764
hmgcl
3-hydroxy-3-methylglutaryl-CoA lyase.
      
 0.754
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
      
 0.704
slc25a19
Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.692
mthfr
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
      
 0.680
LOC101171932
Folate receptor.
      
 0.622
msh4
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.622
scoc
Short coiled-coil protein a.
      
 0.620
slc25a26
Solute carrier family 25 member 26; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.612
hmgcll1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.
      
 0.606
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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