STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101158947Bromodomain containing 4. (1504 aa)    
Predicted Functional Partners:
cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.
   
 
 0.798
nsd3
Nuclear receptor binding SET domain protein 3.
   
 0.689
jmjd6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
    
 
 0.687
e2f1
E2F transcription factor 1.
    
 
 0.680
taf7l
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
    
 
 0.676
dmap1
DNA methyltransferase 1 associated protein 1.
    
 
 0.665
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.
    
 
 0.620
yeats4
YEATS domain containing 4.
    
 
 0.620
LOC101156841
Transcription initiation factor TFIID subunit.
    
 
 0.620
trip12
Thyroid hormone receptor interactor 12.
    
   0.609
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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