Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
neurl4Neuralized E3 ubiquitin protein ligase 4. (1598 aa)    
Predicted Functional Partners:
mapk6
Mitogen-activated protein kinase 6.
    
 
 0.943
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 
 0.932
cep97
Centrosomal protein 97.
    
 
 0.931
LOC101156156
Uncharacterized protein.
     
 0.823
LOC101165876
Ubiquitin protein ligase E3A.
    
 
 0.816
ccp110
Uncharacterized protein.
    
 
 0.798
LOC101171642
Uncharacterized protein.
    
 
 0.798
cep120
Centrosomal protein 120.
    
 0.767
elp5
Elongator acetyltransferase complex subunit 5.
      
 0.755
fbf1
Uncharacterized protein.
      
 0.725
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.