Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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[Homology]
Score
edaEctodysplasin A; Belongs to the tumor necrosis factor family. (364 aa)    
Predicted Functional Partners:
edar
Tumor necrosis factor receptor superfamily member EDAR; Receptor for EDA (By similarity). May mediate the activation of NF-kappa-B and JNK.
    
 0.999
pln
Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
    
   0.920
edaradd
EDAR-associated death domain.
     
 0.868
tnfrsf19
Tumor necrosis factor receptor superfamily, member 19.
    
 0.833
ENSORLP00000041652
TNFR-Cys domain-containing protein.
    
 0.833
prepl
Prolyl endopeptidase like.
      
 0.759
aktip
Akt interacting protein.
      
 0.756
camkmt
Calmodulin-lysine N-methyltransferase.
      
 0.749
ENSORLP00000026634
Uncharacterized protein.
      
 0.706
agmo
Alkylglycerol monooxygenase; Belongs to the sterol desaturase family.
      
 0.704
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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