polh protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

polh

Polymerase (DNA directed), eta. (708 aa)

Predicted Functional Partners:

pcna

0.995

rev1

0.994

rchy1

0.993

rev3l

0.988

rad18

0.988

rps27a

0.966

ubc

0.938

ogg1

0.899

ENSORLP00000028870

0.897

xpa

0.893

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000028870	ogg1	ENSORLP00000028870	ENSORLP00000013488	UmuC domain-containing protein.	8-oxoguanine DNA glycosylase.	0.849
ENSORLP00000028870	pcna	ENSORLP00000028870	ENSORLP00000037447	UmuC domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.991
ENSORLP00000028870	polh	ENSORLP00000028870	ENSORLP00000008189	UmuC domain-containing protein.	Polymerase (DNA directed), eta.	0.897
ENSORLP00000028870	rad18	ENSORLP00000028870	ENSORLP00000040250	UmuC domain-containing protein.	RAD18 E3 ubiquitin protein ligase.	0.840
ENSORLP00000028870	rchy1	ENSORLP00000028870	ENSORLP00000039345	UmuC domain-containing protein.	Ring finger and CHY zinc finger domain containing 1.	0.714
ENSORLP00000028870	rev1	ENSORLP00000028870	ENSORLP00000015289	UmuC domain-containing protein.	REV1 DNA directed polymerase.	0.987
ENSORLP00000028870	rev3l	ENSORLP00000028870	ENSORLP00000018995	UmuC domain-containing protein.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.939
ENSORLP00000028870	rps27a	ENSORLP00000028870	ENSORLP00000038189	UmuC domain-containing protein.	Ribosomal protein S27a.	0.958
ENSORLP00000028870	ubc	ENSORLP00000028870	ENSORLP00000015065	UmuC domain-containing protein.	Ubiquitin B.	0.956
ENSORLP00000028870	xpa	ENSORLP00000028870	ENSORLP00000025771	UmuC domain-containing protein.	Xeroderma pigmentosum, complementation group A.	0.830
ogg1	ENSORLP00000028870	ENSORLP00000013488	ENSORLP00000028870	8-oxoguanine DNA glycosylase.	UmuC domain-containing protein.	0.849
ogg1	pcna	ENSORLP00000013488	ENSORLP00000037447	8-oxoguanine DNA glycosylase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.717
ogg1	polh	ENSORLP00000013488	ENSORLP00000008189	8-oxoguanine DNA glycosylase.	Polymerase (DNA directed), eta.	0.899
ogg1	rad18	ENSORLP00000013488	ENSORLP00000040250	8-oxoguanine DNA glycosylase.	RAD18 E3 ubiquitin protein ligase.	0.675
ogg1	rev1	ENSORLP00000013488	ENSORLP00000015289	8-oxoguanine DNA glycosylase.	REV1 DNA directed polymerase.	0.643
ogg1	rev3l	ENSORLP00000013488	ENSORLP00000018995	8-oxoguanine DNA glycosylase.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.682
ogg1	xpa	ENSORLP00000013488	ENSORLP00000025771	8-oxoguanine DNA glycosylase.	Xeroderma pigmentosum, complementation group A.	0.606
pcna	ENSORLP00000028870	ENSORLP00000037447	ENSORLP00000028870	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	UmuC domain-containing protein.	0.991
pcna	ogg1	ENSORLP00000037447	ENSORLP00000013488	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	8-oxoguanine DNA glycosylase.	0.717
pcna	polh	ENSORLP00000037447	ENSORLP00000008189	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Polymerase (DNA directed), eta.	0.995