Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
vkorc1Vitamin K epoxide reductase complex, subunit 1. (167 aa)    
Predicted Functional Partners:
ggcx
Gamma-glutamyl carboxylase.
   
 
 0.991
nqo1
Flavodoxin_2 domain-containing protein.
     
 0.936
LOC101170381
Flavodoxin_2 domain-containing protein.
     
 0.936
vkorc1l1
Vitamin K epoxide reductase complex, subunit 1-like 1.
  
  
 
0.902
trpt1
tRNA phosphotransferase 1.
   
  
 0.752
LOC101170246
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 
 0.705
prrx1
Paired related homeobox 1a.
      
 0.691
LOC101173208
Phosphoinositide phospholipase C.
      
 0.691
LOC101172964
Phosphoinositide phospholipase C.
      
 0.691
ogfod3
Urotensin-2 receptor 2.
   
  
 0.689
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (12%) [HD]