STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
txndc5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (413 aa)    
Predicted Functional Partners:
LOC101167922
Endoplasmic reticulum oxidoreductase alpha.
   
 0.965
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.965
LOC101166157
Peroxiredoxin 4.
  
 0.941
hspa5
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.875
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.739
gak
Cyclin G associated kinase.
    
 0.693
LOC101160304
Calreticulin.
   
 0.673
LOC101162115
Calreticulin.
   
 0.673
LOC101169735
Calreticulin.
   
 0.673
prdx3
Peroxiredoxin 3.
  
 0.669
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.