Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bcl6bBCL6B transcription repressor. (431 aa)    
Predicted Functional Partners:
bcorl1
BCL6 corepressor-like 1.
    
 0.728
bcor
BCL6 corepressor.
    
 0.728
ncor1
Nuclear receptor corepressor 1.
    
 0.687
ncor2
Nuclear receptor corepressor 2.
    
 0.687
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.
   
 0.582
LOC101167743
Uncharacterized protein.
    
 0.578
LOC101160686
Uncharacterized protein.
    
 0.578
cxcr5
Chemokine (C-X-C motif) receptor 5; Belongs to the G-protein coupled receptor 1 family.
    
 0.577
aicda
Activation-induced cytidine deaminase.
      
 0.523
LOC101173472
Glial cell derived neurotrophic factor b.
      
 0.501
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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