Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100049394TLE family member 3, transcriptional corepressor. (754 aa)    
Predicted Functional Partners:
lef1
Lymphoid enhancer-binding factor 1.
    
 0.713
tbx20
T-box transcription factor 20.
    
 
 0.692
tcf7l1
HMG box domain-containing protein.
    
 0.642
LOC111948314
HMG box domain-containing protein.
    
 0.642
tcf7l2
Transcription factor 7 like 2.
    
 0.642
tcf7
Transcription factor 7.
    
 0.640
en1
Homeobox protein engrailed-like.
    
 
 0.628
ENSORLP00000032097
Uncharacterized protein.
    
  0.623
LOC101166883
X-linked inhibitor of apoptosis.
    
  0.623
LOC101172913
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.578
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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