ewsr1 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ewsr1

EWS RNA-binding protein 1b. (599 aa)

Predicted Functional Partners:

hnrnpm

0.896

dhx9

0.793

LOC101167445

0.785

tardbp

0.785

hnrnpk

0.746

LOC101167466

0.746

polr2g

0.709

taf12

0.686

POLR2E

0.684

cirbp

0.679

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101167445	LOC101167466	ENSORLP00000004481	ENSORLP00000029054	TAR DNA binding protein.	Heterogeneous nuclear ribonucleoprotein K, like.	0.707
LOC101167445	POLR2E	ENSORLP00000004481	ENSORLP00000019213	TAR DNA binding protein.	RNA polymerase II subunit E.	0.409
LOC101167445	dhx9	ENSORLP00000004481	ENSORLP00000009349	TAR DNA binding protein.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.579
LOC101167445	ewsr1	ENSORLP00000004481	ENSORLP00000008429	TAR DNA binding protein.	EWS RNA-binding protein 1b.	0.785
LOC101167445	hnrnpk	ENSORLP00000004481	ENSORLP00000006506	TAR DNA binding protein.	Heterogeneous nuclear ribonucleoprotein K.	0.707
LOC101167445	hnrnpm	ENSORLP00000004481	ENSORLP00000028445	TAR DNA binding protein.	Heterogeneous nuclear ribonucleoprotein M.	0.714
LOC101167445	tardbp	ENSORLP00000004481	ENSORLP00000038752	TAR DNA binding protein.	TAR DNA binding protein, like.	0.901
LOC101167466	LOC101167445	ENSORLP00000029054	ENSORLP00000004481	Heterogeneous nuclear ribonucleoprotein K, like.	TAR DNA binding protein.	0.707
LOC101167466	cirbp	ENSORLP00000029054	ENSORLP00000019322	Heterogeneous nuclear ribonucleoprotein K, like.	Cold inducible RNA binding protein b.	0.688
LOC101167466	dhx9	ENSORLP00000029054	ENSORLP00000009349	Heterogeneous nuclear ribonucleoprotein K, like.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.675
LOC101167466	ewsr1	ENSORLP00000029054	ENSORLP00000008429	Heterogeneous nuclear ribonucleoprotein K, like.	EWS RNA-binding protein 1b.	0.746
LOC101167466	hnrnpk	ENSORLP00000029054	ENSORLP00000006506	Heterogeneous nuclear ribonucleoprotein K, like.	Heterogeneous nuclear ribonucleoprotein K.	0.901
LOC101167466	hnrnpm	ENSORLP00000029054	ENSORLP00000028445	Heterogeneous nuclear ribonucleoprotein K, like.	Heterogeneous nuclear ribonucleoprotein M.	0.983
LOC101167466	tardbp	ENSORLP00000029054	ENSORLP00000038752	Heterogeneous nuclear ribonucleoprotein K, like.	TAR DNA binding protein, like.	0.707
POLR2E	LOC101167445	ENSORLP00000019213	ENSORLP00000004481	RNA polymerase II subunit E.	TAR DNA binding protein.	0.409
POLR2E	cirbp	ENSORLP00000019213	ENSORLP00000019322	RNA polymerase II subunit E.	Cold inducible RNA binding protein b.	0.553
POLR2E	ewsr1	ENSORLP00000019213	ENSORLP00000008429	RNA polymerase II subunit E.	EWS RNA-binding protein 1b.	0.684
POLR2E	hnrnpm	ENSORLP00000019213	ENSORLP00000028445	RNA polymerase II subunit E.	Heterogeneous nuclear ribonucleoprotein M.	0.498
POLR2E	polr2g	ENSORLP00000019213	ENSORLP00000003930	RNA polymerase II subunit E.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.999
POLR2E	taf12	ENSORLP00000019213	ENSORLP00000027474	RNA polymerase II subunit E.	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.886