Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SRCTyrosine-protein kinase. (544 aa)    
Predicted Functional Partners:
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
  
 
0.976
LOC101169984
Receptor protein-tyrosine kinase.
  
 
0.969
egfr
Receptor protein-tyrosine kinase.
    
0.968
syk
Tyrosine-protein kinase.
  
0.968
cttn
Cortactin.
    
 0.966
LOC101155648
Hematopoietic cell-specific Lyn substrate 1.
    
 0.966
esr1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 0.963
LOC101162818
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
    
 0.962
ptk2
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
0.962
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.961
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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