Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
sipa1l3Signal-induced proliferation-associated 1 like 3. (1755 aa)    
Predicted Functional Partners:
ap5b1
Adaptor related protein complex 5 subunit beta 1.
      
 0.605
LOC101162607
Leucine zipper, putative tumor suppressor family member 3b.
    
 0.565
LOC101167529
RAP1A, member of RAS oncogene family b.
    
 0.548
LOC101172864
Uncharacterized protein.
    
 0.548
LOC101171247
RAP1A, member of RAS oncogene family a.
    
 0.548
lzts2
Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family.
    
 0.538
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18.
   
  
 0.509
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic).
   
 0.491
RAP2B
RAP2B, member of RAS oncogene family.
    
 0.469
rap2c
RAP2C, member of RAS oncogene family.
    
 0.469
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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