STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brinp1Bone morphogenetic protein/retinoic acid inducible neural-specific 1. (761 aa)    
Predicted Functional Partners:
sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 
 0.663
smpdl3a
Acid sphingomyelinase-like phosphodiesterase.
   
  
 0.651
LOC101168279
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
      
 0.622
col9a1
Collagen, type IX, alpha 1b.
      
 0.587
gnai3
Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]
   
  
 0.567
ENSORLP00000040040
Uncharacterized protein.
      
 0.560
pigg
Phosphatidylinositol glycan anchor biosynthesis class G.
      
 0.532
wdr35
WD repeat-containing protein 35.
      
 0.529
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
      
 0.504
nsmaf
Neutral sphingomyelinase (N-SMase) activation associated factor.
      
 0.459
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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