proc protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

proc

Protein C (inactivator of coagulation factors Va and VIIIa), a. (436 aa)

Predicted Functional Partners:

LOC101170246

0.983

stil

0.921

serpind1

0.841

fga

0.786

fgb

0.759

serpinf2

0.747

LOC101174928

0.738

LOC101166425

0.738

ggcx

0.719

pros1

0.710

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101166425	LOC101170246	ENSORLP00000030665	ENSORLP00000033975	Coagulation factor V; Belongs to the multicopper oxidase family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.890
LOC101166425	LOC101174928	ENSORLP00000030665	ENSORLP00000003708	Coagulation factor V; Belongs to the multicopper oxidase family.	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	0.505
LOC101166425	fga	ENSORLP00000030665	ENSORLP00000003045	Coagulation factor V; Belongs to the multicopper oxidase family.	Fibrinogen alpha chain.	0.472
LOC101166425	fgb	ENSORLP00000030665	ENSORLP00000003101	Coagulation factor V; Belongs to the multicopper oxidase family.	Fibrinogen beta chain.	0.510
LOC101166425	proc	ENSORLP00000030665	ENSORLP00000008456	Coagulation factor V; Belongs to the multicopper oxidase family.	Protein C (inactivator of coagulation factors Va and VIIIa), a.	0.738
LOC101166425	pros1	ENSORLP00000030665	ENSORLP00000006077	Coagulation factor V; Belongs to the multicopper oxidase family.	Protein S.	0.710
LOC101166425	serpind1	ENSORLP00000030665	ENSORLP00000002789	Coagulation factor V; Belongs to the multicopper oxidase family.	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.	0.529
LOC101166425	stil	ENSORLP00000030665	ENSORLP00000017607	Coagulation factor V; Belongs to the multicopper oxidase family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.638
LOC101170246	LOC101166425	ENSORLP00000033975	ENSORLP00000030665	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor V; Belongs to the multicopper oxidase family.	0.890
LOC101170246	LOC101174928	ENSORLP00000033975	ENSORLP00000003708	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	0.890
LOC101170246	fga	ENSORLP00000033975	ENSORLP00000003045	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Fibrinogen alpha chain.	0.997
LOC101170246	fgb	ENSORLP00000033975	ENSORLP00000003101	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Fibrinogen beta chain.	0.992
LOC101170246	ggcx	ENSORLP00000033975	ENSORLP00000011804	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Gamma-glutamyl carboxylase.	0.837
LOC101170246	proc	ENSORLP00000033975	ENSORLP00000008456	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Protein C (inactivator of coagulation factors Va and VIIIa), a.	0.983
LOC101170246	serpind1	ENSORLP00000033975	ENSORLP00000002789	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.	0.990
LOC101170246	serpinf2	ENSORLP00000033975	ENSORLP00000006091	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.828
LOC101170246	stil	ENSORLP00000033975	ENSORLP00000017607	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.998
LOC101174928	LOC101166425	ENSORLP00000003708	ENSORLP00000030665	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	Coagulation factor V; Belongs to the multicopper oxidase family.	0.505
LOC101174928	LOC101170246	ENSORLP00000003708	ENSORLP00000033975	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.890
LOC101174928	fga	ENSORLP00000003708	ENSORLP00000003045	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	Fibrinogen alpha chain.	0.471