close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbckTBC1 domain containing kinase. (889 aa)    
Predicted Functional Partners:
c6h12orf4
Zgc:154077.
    
 
 0.681
cln3
Battenin.
      
 0.591
Cln5
CLN5 intracellular trafficking protein.
      
 0.582
nme6
Nucleoside diphosphate kinase.
   
  
 0.570
ppp1r21
Protein phosphatase 1, regulatory subunit 21.
    
 
 0.567
LOC101175475
Canopy FGF signaling regulator 2.
      
 0.558
ppt1
Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).
      
 0.501
mfsd8
Major facilitator superfamily domain containing 8.
      
 0.501
cln6
CLN6 transmembrane ER protein a.
      
 0.501
LOC101175251
MOB kinase activator 1Bb.
      
 0.400
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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