LOC101162386 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC101162386

SIX homeobox 5. (928 aa)

Predicted Functional Partners:

LOC100049216

0.678

eya4

0.673

LOC101169441

0.673

eya1

0.673

LOC101159324

0.636

dach

0.621

snai2

0.466

LOC101156270

0.464

myog

0.441

aurka

0.424

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100049216	LOC101162386	ENSORLP00000011778	ENSORLP00000008488	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 5.	0.678
LOC100049216	dach	ENSORLP00000011778	ENSORLP00000014055	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Ski_Sno domain-containing protein.	0.646
LOC101156270	LOC101159324	ENSORLP00000045059	ENSORLP00000045539	Uncharacterized protein.	DM1 locus, WD repeat containing.	0.504
LOC101156270	LOC101162386	ENSORLP00000045059	ENSORLP00000008488	Uncharacterized protein.	SIX homeobox 5.	0.464
LOC101159324	LOC101156270	ENSORLP00000045539	ENSORLP00000045059	DM1 locus, WD repeat containing.	Uncharacterized protein.	0.504
LOC101159324	LOC101162386	ENSORLP00000045539	ENSORLP00000008488	DM1 locus, WD repeat containing.	SIX homeobox 5.	0.636
LOC101162386	LOC100049216	ENSORLP00000008488	ENSORLP00000011778	SIX homeobox 5.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.678
LOC101162386	LOC101156270	ENSORLP00000008488	ENSORLP00000045059	SIX homeobox 5.	Uncharacterized protein.	0.464
LOC101162386	LOC101159324	ENSORLP00000008488	ENSORLP00000045539	SIX homeobox 5.	DM1 locus, WD repeat containing.	0.636
LOC101162386	LOC101169441	ENSORLP00000008488	ENSORLP00000041634	SIX homeobox 5.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.673
LOC101162386	aurka	ENSORLP00000008488	ENSORLP00000007079	SIX homeobox 5.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.424
LOC101162386	dach	ENSORLP00000008488	ENSORLP00000014055	SIX homeobox 5.	Ski_Sno domain-containing protein.	0.621
LOC101162386	eya1	ENSORLP00000008488	ENSORLP00000045154	SIX homeobox 5.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.673
LOC101162386	eya4	ENSORLP00000008488	ENSORLP00000028671	SIX homeobox 5.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.673
LOC101162386	myog	ENSORLP00000008488	ENSORLP00000019914	SIX homeobox 5.	Myogenin.	0.441
LOC101162386	snai2	ENSORLP00000008488	ENSORLP00000021850	SIX homeobox 5.	Snail family zinc finger 2.	0.466
LOC101169441	LOC101162386	ENSORLP00000041634	ENSORLP00000008488	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 5.	0.673
LOC101169441	dach	ENSORLP00000041634	ENSORLP00000014055	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Ski_Sno domain-containing protein.	0.646
aurka	LOC101162386	ENSORLP00000007079	ENSORLP00000008488	Aurora kinase A; Belongs to the protein kinase superfamily.	SIX homeobox 5.	0.424
dach	LOC100049216	ENSORLP00000014055	ENSORLP00000011778	Ski_Sno domain-containing protein.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.646