Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
orla-ubaClassical MHC class I molecule, alpha-chain; Belongs to the MHC class I family. (360 aa)    
Predicted Functional Partners:
ENSORLP00000035474
Ig-like domain-containing protein.
    
  0.913
LOC101174715
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
     
  0.900
LOC100125537
Uncharacterized protein.
    
 0.898
rpa2
Replication protein A2.
   
 0.880
pdia3
Protein disulfide-isomerase.
    
 0.841
LOC101160304
Calreticulin.
    
 0.814
LOC101162115
Calreticulin.
    
 0.814
LOC101169735
Calreticulin.
    
 0.814
LOC101165241
Protein disulfide-isomerase.
    
  0.766
LOC101173540
Cd8 beta.
     
 0.762
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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