Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gipc3GIPC PDZ domain containing family, member 3. (334 aa)    
Predicted Functional Partners:
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
   
 
 0.804
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
   
 
 0.799
LOC101175525
Myosin VIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.715
myo6
Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.715
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 
 0.623
brca2
BRCA2 DNA repair associated.
      
 0.609
LOC101155037
Transforming growth factor beta; Belongs to the TGF-beta family.
     
  0.582
agmat
Agmatine ureohydrolase (agmatinase); Belongs to the arginase family.
      
 0.563
LOC101157631
Transforming growth factor beta; Belongs to the TGF-beta family.
     
 0.561
tgfbr3
Transforming growth factor, beta receptor III.
    
  0.555
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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