Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
limk2LIM domain kinase 2. (654 aa)    
Predicted Functional Partners:
cfl1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.987
LOC101159957
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 0.987
LOC101164501
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.980
LOC101172697
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
0.947
rock1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
0.947
LOC101159717
Rho-associated, coiled-coil containing protein kinase 2b; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
0.943
LOC101162943
LIM domain kinase 1b.
  
  
 
0.903
LOC101168972
LIM domain kinase 1a.
  
  
 
0.902
PAK3
Non-specific serine/threonine protein kinase.
    
0.879
pak1
Non-specific serine/threonine protein kinase.
    
0.879
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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