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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK3Non-specific serine/threonine protein kinase. (590 aa)    
Predicted Functional Partners:
nck1
Cytoplasmic protein.
    
 0.975
nck2
Cytoplasmic protein.
    
 0.975
limk2
LIM domain kinase 2.
    
0.960
CDC42
Cell division cycle 42.
   
 0.960
LOC101164400
Uncharacterized protein.
   
 0.960
LOC101162943
LIM domain kinase 1b.
    
0.951
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
0.939
LOC101175525
Myosin VIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
  0.939
LOC101161831
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
  0.938
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
    
 0.933
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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