Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAK3Non-specific serine/threonine protein kinase. (590 aa)    
Predicted Functional Partners:
nck1
Cytoplasmic protein.
    
 0.980
nck2
Cytoplasmic protein.
    
 0.980
CDC42
Cell division cycle 42.
   
 0.971
LOC101164400
Uncharacterized protein.
   
 0.971
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
0.958
LOC101156802
Rho guanine nucleotide exchange factor (GEF) 7b.
   
 0.954
LOC101166510
Rho guanine nucleotide exchange factor (GEF) 7a.
   
 0.954
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
   
 0.954
LOC101175525
Myosin VIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
  0.938
myo6
Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
  0.938
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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