Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
man2b2Alpha-mannosidase. (1078 aa)    
Predicted Functional Partners:
man2c1
Mannosidase, alpha, class 2C, member 1.
     
0.948
man2b1
Alpha-mannosidase.
     
0.914
manba
Mannosidase, beta A, lysosomal.
   
 
 0.829
LOC101168962
Guanine nucleotide binding protein (G protein), alpha 14a.
      
 0.724
siae
Sialic acid acetylesterase.
    
 
 0.693
gla
Alpha-galactosidase.
   
 
 0.664
naga
Alpha-galactosidase.
   
 
 0.664
H2LFR3_ORYLA
B30.2/SPRY domain-containing protein.
      
 0.620
LOC101167368
Uncharacterized protein.
      
 0.620
LOC101165576
Tripartite motif containing 69.
      
 0.620
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (12%) [HD]