Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100125506Retinoid x receptor, beta b. (444 aa)    
Predicted Functional Partners:
pparg
Uncharacterized protein.
   
0.979
nr1h3
Nuclear receptor subfamily 1, group H, member 3.
   
 0.922
rxra
Retinoid X receptor, alpha a.
  
  
 
0.908
nr1h4
Nuclear receptor subfamily 1, group H, member 4.
   
 0.866
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.845
ppard
Uncharacterized protein.
    
 0.828
ncor1
Nuclear receptor corepressor 1.
    
 0.823
ncor2
Nuclear receptor corepressor 2.
    
 0.823
PPARA
Peroxisome proliferator-activated receptor alpha b.
   
 0.781
ncoa6
Nuclear receptor coactivator 6.
   
 0.777
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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