Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101168720Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.938
Frat2
Glycogen synthase kinase binding protein.
    
 0.896
apc2
APC regulator of WNT signaling pathway 2.
    
 0.877
apc
APC regulator of WNT signaling pathway.
    
 0.877
nfe2l2
Nuclear factor, erythroid 2-like 2a.
    
 0.874
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
   
 0.871
axin1
Axin 1.
   
 0.860
LOC101155494
Uncharacterized protein.
   
 0.860
fbxw11
F-box and WD repeat domain containing 11a.
    
 0.848
LOC101159441
Axin 2 (conductin, axil).
   
 0.845
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (16%) [HD]